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Interfacial transport

Hydrogen therapy for ischemic injuries

Wireless, portable hydrogel electrochemical systems provide on-demand hydrogen generation and localized delivery, offering a targeted therapeutic solution to mitigate oxidative stress in ischemia-reperfusion injuries while establishing a platform technology for precision gas therapy and controlled drug delivery.

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Fig. 1: H2 delivery via a hydrogel-based electrochemical cell for ischemia-reperfusion injuries.

References

  1. Ohsawa, I. et al. Nat. Med. 13, 688–694 (2007).

    Article  CAS  PubMed  Google Scholar 

  2. Nie, C. et al. Life Sci. 272, 119248 (2021).

    Article  CAS  PubMed  Google Scholar 

  3. Zhang, Y. et al. Sci. Rep. 6, 23742 (2016).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Chen, S. et al. Nat. Commun. 13, 5684 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Chen, H. et al. Nano Lett. 22, 229–237 (2022).

    Article  CAS  PubMed  Google Scholar 

  6. Yang, N. et al. Nat. Commun. 13, 2336 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Li, W. et al. Nat. Chem. Eng. https://doi.org/10.1038/s44286-025-00259-x (2025).

    Article  PubMed  PubMed Central  Google Scholar 

  8. Xu, M. et al. Exploration 4, 20220106 (2024).

    Article  PubMed  Google Scholar 

Download references

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Correspondence to Yunlong Zhao.

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Ren, X., Zhao, Y. Hydrogen therapy for ischemic injuries. Nat Chem Eng 2, 467–469 (2025). https://doi.org/10.1038/s44286-025-00258-y

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