Fig. 1: Partial least squares-discriminant analyses using serum metabolites of women with normal pregnancies and threatened miscarriages. | npj Women's Health

Fig. 1: Partial least squares-discriminant analyses using serum metabolites of women with normal pregnancies and threatened miscarriages.

From: Untargeted metabolomics reveals key pathways in miscarriage: steroid, folate, fatty acid & glycosaminoglycan metabolism

Fig. 1

a The partial least squares-discriminant analysis (PLS-DA) of serum metabolites in patients with threatened miscarriage (TM) vs those with normal pregnancies (NP), with the PLSDA showing separation into 2 distinct clusters (5 fold cross-validation with 5 principal components – R2 = 0.99, Q2 = 0.65, classification accuracy = 0.99). b The PLS-DA of metabolites in patients with threatened miscarriage who eventually miscarried (TMMC) vs those who had ongoing pregnancies (TMO). PLSDA shows poor separation (5 fold cross-validation with 5 principal components – R2 = 0.98, Q2 = 0.22, classification accuracy = 0.66).

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