Table 3 Predictive models for endometriosis postoperative recurrence published in the literature
From: Rethinking endometriosis recurrence: from clinical challenge to biological opportunity
Recurrence predictive model | Sample size (R/NR) | Recurrence assessmenta | Follow-upb (months) | Parameters included in the model | Sens. (%) | Spec. (%) | AUC | Accur. (%) |
|---|---|---|---|---|---|---|---|---|
Based on patient characteristics | ||||||||
Holdsworth-Carson et al.58 | 503 (221/282) | Laparoscopy (with self-reported previous laparoscopy) | NA | Age ER attendance Adhesions Eczema Pararectal space lesion | NA | NA | 0.668 | NA |
Holdsworth-Carson et al.58 | 382 (94/288) | Laparoscopy | NA | Adenomyosis Diastolic blood pressure Uterine fibroids Adhesions Age of menarche | NA | NA | 0.617 | NA |
Huang et al.67 | 289 (49/240) | Symptomatic Pelvic exam CA125 > 35 U/mL TVUS | 12 | rASRM score | 57.1 | 94.2 | 0.79 | 87.9 |
Su and Xie50 | 212 (36/176) | Symptomatic, supported by pelvic exam or ultrasonography or CA125 increase | 24 | Age Bilateral cysts rASRM staging TNFα serum levels Postop. medication | 89.4 | 83.7 | 0.895 | NA |
Li et al.68 | 164 (46/118) | TVUS Pelvic exam | 12 | History of abortion Abnormal uterine bleeding rASRM staging Posterior fornix tenderness | 71 | 76 | 0.802 | 73 |
Incorporating proteomic biomarkers | ||||||||
Shen et al.106 | 109 (53/56) | TVUS or Laparoscopy | 32 | PRB levels (IHC) NFκB-p65 levels (IHC) | 80 | 82 | NA | NA |
Shen et al.107 | 88 (43/45) | TVUS or Laparoscopy | 32 | SLIT levels (IHC) Presence of adhesions PRB levels (IHC) NFκB-p65 levels (IHC) | 86 | 87 | NA | NA |
Yuan et al.105 | 109 (53/56) | Ultrasonography or Laparoscopy | 32 | COX2 levels (IHC) Previous medication Presence of adhesion | 72.5 | 72.4 | NA | NA |
