Fig. 4: Macrophages, neutrophils and DCs infiltrate testes at 23 dpi.
From: CD8+ T cells promote ZIKV clearance and mitigate testicular damage in mice
Cell count and myeloid cells for A the spleen, B the inguinal lymph nodes, C the mesenteric lymph nodes and D testes. Mice were infected intraperitoneally with a target dose of 3log10 PFU. In the experiment related to this figure, 5 mice were used for the PBS group, 5 mice for the 7 dpi group, and 6 mice for the 23 dpi group. Red bars show ZIKV-infected mice, and black bars denote uninfected baseline controls. Statistical significance was assessed with one-way ANOVA with Sidak’s multiple comparison correction. Comparisons were made between each of the groups and only significant results are shown. Bars show mean and error bars represent standard error of the mean. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.
