Table 1 Proteins that were changed in levels at 3 dpi, 5 dpi, and 31 dpi in infected males
From: SARS-CoV-2 infection results in a unique lung proteome long after virus resolution in the hamster
Mean log2 Fold Change | ||||
|---|---|---|---|---|
Protein (Gene) | 3 dpi | 5 dpi | 31 dpi | Potential role in lungs or disease association |
Allograft inflammatory factor 1 (Aif1) | 2.86 F: 3.01 | 2.09 F: 2.73 | –2.30 | Increased in Olfactory bulb of SARS-CoV-2 infected hamsters45 |
Specifically androgen-regulated gene protein isoform X1; X2 (CUNH1orf116) | –3.19 | –4.35 F: –2.06 | –2.99 | None found |
Glia maturation factor gamma (Gmfg) | –2.70 | 6.49 F: 6.36 | –2.24 | .Mediates neutrophil and T lymphocyte migration via regulation of actin cytoskeletal reorganization46,47 |
LIM and calponin homology domains-containing protein 1 isoform X7; X10; X9; (Limch1) | –2.73 F: -2.5 | –3.84 F: –2.6 | –3.30 | None found |
Epidermal growth factor receptor kinase substrate 8-like protein 2 (LOC101830673) | –2.07 | –2.50 | –2.18 | None found |
Phosphatase and actin regulator 4 (Phactr4) | –2.95 | –3.17 | –2.12 | In mice, interacts with actin and protein phosphatase 148 |
Protein scribble homolog (Scrib) | –3.07 | –4.23 F: –3.47 | –2.06 | Lung cell morphogenesis49 |
Delta-sarcoglycan (Sgcd) | –4.52 F: –2.07 | –5.95 | –3.26 | Airway responsiveness50 |
Transmembrane protein 100 (Tmem100) | –3.80 | –4.65 F: -3.66 | –2.56 | Lung endothelial cells with roles in angiogenesis and vascular morphogenesis and integrity51 |
