Table 1 Molecular characteristics of hmAbs

From: Potent neutralization by a RBD antibody with broad specificity for SARS-CoV-2 JN.1 and other variants

mAb

VH

DH

JH

Isotype

% mutation (AA)

HCDR3 length (AA)

VL

JL

% mutation (AA)

LCDR3 length (AA)

1301B7

IGHV1-69

IGHD4-17

IGHJ6

IgG1

20.0

21

IGLV1-40

IGLJ2

14.4

10

1301A8

IGHV1-69

IGHD1-26

IGHJ2

IgA1

16.7

18

IGKV4-1

IGKJ2

6.4

9

1300F12

IGHV3-66

IGHD3-16

IGHJ6

IgA2

14.4

16

IGLV1-51

IGLJ1

11.2

12

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