Fig. 1: Differentially expressed cytokines, chemokines, and growth factors among patient groups: ZIKV (green) and CHIKV (blue) monoinfected, Coinfected (orange), and noninfected controls (grey).
From: Coinfection with chikungunya and Zika results in mild disease and distinct inflammatory response
Of the 45 immune mediators quantified in patients’ sera, 12 were differentially expressed and are presented as follows: CCL2 (a), CCL4 (b), CCL5 (c), EGF (d), CXCL1 (e), CXCL10 (f), CXCL12 (g), SCF (h), IL-1RA (i), IL-8 (j), IFN-α (k), and IFN-γ (l). Each dot represents one participant; the boxes indicate the median and interquartile ranges (25%–75%), and the lines denote the minimum and maximum values. Comparisons were made using the Kruskal-Wallis test followed by Dunn’s test. The p-value is presented for each specific comparison.
