Fig. 1: Characterization of RABV-positive skin cells at the intramuscular or intradermal inoculation site of experimentally inoculated mice and in bite/scratch marks of naturally infected dogs. | npj Viruses

Fig. 1: Characterization of RABV-positive skin cells at the intramuscular or intradermal inoculation site of experimentally inoculated mice and in bite/scratch marks of naturally infected dogs.

From: Exploring the role of infected keratinocytes during rabies virus infection

Fig. 1

Tissues of mice (a) and dogs (b) were investigated for general morphology by hematoxylin and eosin (H&E) staining, for the presence of viral proteins by immunohistochemistry (IHC, red) and immunofluorescence (IF, pink), and for the presence of viral RNA by in situ hybridization (ISH, pink). An antibody against keratin-14 (K-14) was used to identify keratinocytes in IHC and IF, and Hoechst was used to stain the cell nuclei in IF. Scale bars represent 50 µm for panel (a) and 100 µm for panel (b).

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