Fig. 1: Retinal brain connections underlying the effects of light on visual functions.
From: Beyond vision: effects of light on the circadian clock and mood-related behaviours
Image-forming visual functions of rods and cones projecting to the LGN and the tectum are shown in green. IpRGCs project via the RHT (orange) to various brain areas for non-image-forming visual functions such as photoentrainment and mood-related behaviours. DRN dorsal raphe nuclei, IGL intergeniculate leaflet, ipRGC intrinsically photosensitive retinal ganglion cell, LGN lateral geniculate nucleus, LH lateral hypothalamus, LHb lateral habenula, mPFC medial prefrontal cortex, NAc nucleus accumbens, PHb perihabenula, RHT retinohypothalamic tract, SCN suprachiasmatic nuclei, SPZ subparaventricular zone, VLPO ventrolateral preoptic area, VTA ventral tegmental area.
