Fig. 9: The homeostatic-circadian-light (HCL) model. | npj Biological Timing and Sleep

Fig. 9: The homeostatic-circadian-light (HCL) model.

From: The complexity and commonness of the two-process model of sleep regulation from a mathematical perspective

Fig. 9: The homeostatic-circadian-light (HCL) model.The alternative text for this image may have been generated using AI.

Adapted from ref. 21. In the HCL model, light, gated by sleep, is fed into a model which captures the phase and dose response of light on the circadian pacemaker48. The circadian pacemaker then results in a wake propensity rhythm which, when combined with sleep homeostasis, results in patterns of sleep and wake.

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