Fig. 1: Deletion of THRB has only modest overall effects on the liver transcriptome. | npj Metabolic Health and Disease

Fig. 1: Deletion of THRB has only modest overall effects on the liver transcriptome.

From: Thyroid hormone receptor beta (THRB) dependent regulation of diurnal hepatic lipid metabolism in adult male mice

Fig. 1

A Experimental design and modes of DEG analysis. B Volcano plot of global differentially expressed genes (i.e., DEGs irrespective of sampling time; padj < 0.05). Red and blue represent significantly UP- and DOWN-regulated genes, respectively. C Comparison of global DEG numbers between livers from T3- and MMI-treated and THRB-deficient animals stratified for significance threshold. N = 3 independent samples per time point and condition for THRBWT and THRBKO mice. The mouse picture described in A was obtained from Biorender.

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