Fig. 3: Plasma exposure (mean±SD) of A-chain following i.v. bolus administration to rat at three different doses.
From: Chain splitting of insulin: an underlying mechanism of insulin resistance?
The left panel shows absolute concentrations, the right panel shows dose-normalized values. Vd: 0.26 L/kg, 95% CI [0.17;0.53], t½: 1.2 min, 95% CI [1.0;1.5], Cl: 0.14 L/kg/min, 95% CI [0.09;0.20].
