Table 2 Studies included in meta-analysis

From: The effect of high-sugar feeding on rodent metabolic phenotype: a systematic review and meta-analysis

First Author	Species/ Strain	Sugar	Control Diet Type	StartAge (wks)	n	Duration (wks)	Sugar (% E)	Fat (% E)	BW	EI	LC	LT	ALT	LW	FG	FI	GlucoseAUC	Leptin	PT	PC
Tillman et al. ³⁹	C57BL/6H Mice	Fructose	Non-standard	3	7–10	17	61	13	+	+									+
	C57BL/6 J Mice	Sucrose	Non-standard	3	82 sugar 24 control	23	60	13	+
	C57BL/6 J Mice	Fructose	Non-standard	3	64 sugar 24 control	23	60	13	+
Surwit et al. ⁴⁰	A/J Mice	Sucrose	Non-standard	4	30	20	55	11	+	+					+	+
Surwit et al. ⁴⁰	C57BL/6 J Mice	Sucrose	Non-standard	4	30	20	55	11	+	+					+	+
Black et al. ⁴¹	A/J Mice	Sucrose	Non-standard	4	10	20	73	11	+	+
Black et al. ⁴¹	C57BL/6 J Mice	Sucrose	Non-standard	4	10	20	73	11	+	+
Donovan et al. ⁴²	C57BL/6 J Mice	Sucrose	Non-standard	6	5–10	26	35	10	+				+						+	+
Pagliassotti et al. ⁴³	Wistar Rat	Sucrose	Non-standard	5	32 sugar 31 control	8	68	12	+	+
Rodrigues Neto Angeloco et al. ⁴⁴	Wistar Rat	Sucrose	AIN-93G	4	8	8	59.8	7	+	+
Camelo et al. ⁴⁵	C57BL/6 J Mice	Fructose	AIN-93M	12	10	8	50	10	+						+				+	+
Schipke et al. ⁴⁶	C57BL/6 N Mice	Sucrose	Non-standard	6	8–10	32	35	10	+	+					+		+		+	+
Chang et al. ⁴⁷	Wistar Rat	Sucrose	Non-standard	4	10	6	40	12	+	+	+	+		+						+
Huang et al. ⁴⁸	Sprague Dawley Rat	Fructose	Brown Chow	8	6–10	20	66	12	+	+					+	+		+	+	+
Jeon et al. ⁴⁹	Wistar Rat	Fructose	AIN-93G	9	10	13	66	7	+	+		+	+	+					+
Maekawa et al. ⁵⁰	Wistar Rat	Sucrose	Brown Chow	8	7–12	23	38.5	12.6	+	+					+	+	+	+	+
Martínez-Carrillo et al. ⁵¹	BALB/c mice	Sucrose	AIN-93G	4	6	12	30	4.3							+			+
Woodie et al. ⁵²	Sprague Dawley Rat	Fructose	Brown Chow	7	10 sugar 11 control	16	55	20	+	+				+	+	+			+
Kimura et al. ⁵³	C57BL/6 J Mice	Sucrose	Non-standard	35	8	29	55	17	+	+	+	+		+	+	+	+	+	+	+
Brownlow et al. ⁵⁴	A/J Mice	Sucrose	Non-standard	4	10	22	50	11	+	+					+	+
Brownlow et al. ⁵⁴	C57BL/6 J Mice	Sucrose	Non-standard	4	10	22	50	11	+	+					+	+
Ryu et al. ⁵⁵	ICR Mice	Sucrose	AIN-76	4	7-21	16	73	1.7	+	+	+	+			+	+		+		+
Ryu et al. ⁵⁶	Sprague Dawley Rat	Sucrose	AIN-76	4	6	8	73	1.7	+	+		+							+	+
Oscai et al. ⁵⁷	Wistar Rat	Sucrose	Brown Chow	3	16 sugar 8 control	58	55	8	+	+
Spezani et al. ⁵⁸	C57BL/6 J Mice	Fructose	AIN-93M	12	5–10	24	45	14	+	+					+	+		+	+	+
Pompili et al. ⁵⁹	C57BL/6 J Mice	Fructose	Brown Chow	3	10 sugar control	75	60.5	16.4	+
Dziadek et al. ⁶⁰	Wistar Rat	Fructose	AIN-93G	6	8	18	63	7	+				+	+	+				+	+
Tamer et al. ⁶¹	C57BL/6 J Mice	Fructose	AIN-93M	10	10 sugar 8 control	25	35	10	+	+			+	+	+	+			+
de Souza Marinho et al. ¹⁵	C57BL/6 J Mice	Fructose	AIN-93G	12	20	24	50	14	+	+	+	+	+		+	+	+	+	+	+
Nigro et al. ⁶²	C57BL/6 J Mice	Fructose	Non-standard	4	10 sugar 8 control	16	60	20	+	+	+	+		+	+		+		+	+
Sumiyoshi et al. ⁶³	C57BL/6 J Mice	Sucrose	Non-standard	5	6	60	55	14.8	+	+	+	+			+		+	+	+	+
Svop Jensen et al. ⁶⁴	Sprague Dawley Rat	Fructose	Non-standard	12	10	28	60	10	+		+	+	+		+			+	+	+
Guimarães et al. ⁶⁵	C57BL/6 J Mice	Fructose	AIN-93M	12	6 sugar 5 control	20	50	9.4	+	+	+	+		+	+		+		+	+
Motta et al. ⁶⁶	C57BL/6 Mice	Fructose	AIN-93M	12	10	30	55	10	+	+	+				+	+	+		+
Huang et al. ⁶⁷	Sprague Dawley Rat	Fructose	Brown Chow	8	30	20	66	5	+	+					+	+			+	+
de Oliveira Sá et al. ⁶⁸	C57BL/6 Mice	Fructose	AIN-93M	12	10	32	50	14	+										+	+
Kawasaki et al. ⁶⁹	Wistar Rat	Fructose	Non-standard	5	9 sugar 7 control	10	70	7	+			+	+	+	+				+
Kawasaki et al. ⁶⁹	Wistar Rat	Sucrose	Non-standard	35	9 sugar 7 control	10	70	7	+			+	+	+	+				+
Mazzoli, A., et al. ⁷⁰	Wistar Rat	Fructose	Non-standard	4	8	3	30	10.6	+								+		+
Petito, G., et al. ⁷¹	Sprague Dawley Rat	Fructose	Non-standard	4	6	2	30	10.6	+					+			+		+
Petito, G., et al. ⁷¹	Sprague Dawley Rat	Fructose	Non-standard	13	6	2	30	10.6	+					+			+		+
Zhou, X., et al. ⁷²	C57BL/6 J Mice	Fructose	Brown Chow	7	6	12	60	3	+				+		+		+
Aljahdali, B. A., et al. ⁷³	Wistar Rat	Sucrose	Non-standard	7	7	22	60	20	+				+		+	+			+	+
Fryklund, C., et al. ⁷⁴	C57BL/6 J Mice	Sucrose	Non-standard	9	20	4	35	10	+	+		+			+	+
Crescenzo, R., et al. ⁷⁵	Sprague Dawley Rat	Fructose	Brown Chow	13	6	8	30	10.6	+						+	+	+

+ measured, BW body weight, EI Energy Intake, LC Liver Cholesterol, LT Liver Triglycerides, ALT Alanine transaminase, LW Liver Weight, FG Fasting Glucose, FI Fasting Insulin, AUC Glucose Area under the curve, PT Plasma Triglycerides, PC Plasma Cholesterol.

Back to article page

Table 2 Studies included in meta-analysis

Search

Quick links