Fig. 3: Longevity analysis of insulin receptor a (insra) mutant zebrafish.
From: Cave adaptation favors aging resilience in the Mexican tetra
A Zebrafish P211L (insra) mutation using CRISPR/Cas9 strategy. Target site located in exon 3 and specific SNP exchange denoted with a star, adapted from22. B Survival curve of wildtype (WT), homozygote mutants (insra -/-) and heterozygote (insra + /-), in females (C) and males (D). Repeat experiment in independent cohort (E–G).
