Fig. 5: Analysis of gene expression in endothelial cells expressing PA endothelial markers exclusively.
From: Distinct endothelial cells in chronic thromboembolic pulmonary hypertension
a UMAP visualization and clustering of endothelial cells expressing PA endothelial markers from control and CTEPH endothelial cells. Left: UMAP visualization with cells parsed by control vs CTEPH. Right: UMAP visualization with 5 PA endothelial cell clusters shown. b Proportion of PA endothelial cells for each cluster in control and CTEPH. c Heatmap of top 5 markers for each PA endothelial cell cluster. d–g Expression of markers of (d) endothelial thrombotic regulation, (e) endothelial activation, (f) TFG-β signaling, and (g) angiogenesis in PAECs. Control ECs are represented in red and CTEPH ECs are represented in blue.
