Fig. 6: Genetic analyses of proteins of interest.
From: Associations between carotid artery intima-media thickness, traditional risk factors and proteins
A Expression analysis in three relevant arteries for genes of five proteins being significant in the Mendelian randomization (MR) analysis vs the intima-media thickness (IMT). B Heat-map of MR-Wald ratio estimate of selected proteins with traditional risk factors of IMT. Significant levels are expressed as ***, **, * or lack of * if nominal p-value is <0.001, <0.01, < 0.05 or > 0.05. A blank square indicates that no association was estimated because of lack of genetic instruments. C Mediation analysis of the effect of proteins on IMT via SBP using MR.
