Table 1 Participant characteristics according to incident atrial fibrillation status

From: The senescence-inducing factor IGFBP7 and risk of atrial fibrillation: findings from the PREVEND study

Characteristics

No incident AF

Incident AF

P value

 

N = 5730

N = 154

 

IGFBP7 (median, P25–P75), µg/L

84.3 (74.8–95.4)

98.1 (87.3–111.0)

<0.001

Age (mean, SD), years

53.3 (12.0)

65.4 (8.4)

<0.001

Female sex, n (%)

2988 (52.1)

43 (27.9)

<0.001

Height (mean, SD), cm

172.5 (9.5)

175.2 (9.4)

<0.001

Weight (mean, SD), kg

79.2 (14.3)

87.9 (14.6)

<0.001

Relative fat mass, %

32.0 (7.3)

32.4 (6.9)

0.52

Body mass index, kg/m2

26.6 (4.3)

28.6 (4.4)

<0.001

SBP (mean, SD), mm Hg

125.7 (18.7)

136.7 (21.6)

<0.001

Antihypertensive medication, n (%)

1208 (21.1)

89 (57.8)

<0.001

Smoking

  

<0.001

 Current, n (%)

1563 (27.3)

39 (25.3)

 

 Past, n (%)

2401 (41.9)

87 (56.5)

 

Diabetes, n (%)

359 (6.3)

22 (14.4)

<0.001

Myocardial infarction or stroke, n (%)

384 (6.7)

45 (29.2)

<0.001

Heart failure, n (%)

36 (0.6)

14 (9.1)

<0.001

NT-proBNP (median, P25–P75), ng/L

41.0 (21.0–78.0)

153.5 (70.0–304.0)

<0.001

UAE (median, P25–P75), mg/24 h

8.1 (5.9–13.5)

12.2 (7.5–37.7)

<0.001

eGFR (mean, SD), mL/min/1.73 m2

92.5 (16.4)

79.4 (18.2)

<0.001

  1. Continuous variables are presented as mean (standard deviation) or as a median (percentile 25 to percentile 75), and categorical variables as n (%).
  2. AF atrial fibrillation, IGFBP7 insulin-like growth factor binding protein-7, SBP systolic blood pressure, NT-proBNP N-terminal pro-B-type natriuretic peptide, UAE 24-h urinary albumin excretion, eGFR estimated glomerular filtration rate.
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