Fig. 2: Comparison of capillary action for α-syn and PrP.
a Differences in capillary height for native (neg) (n = 12, average: 44.2 mm, stdev: 1.3 mm), spontaneous misfolded solutions (pos) (n = 12, average: 49.1 mm, stdev: 2.0 mm), and buffer only control (n = 12, average: 50.3 mm, stdev: 1.3 mm) for α-syn. b Differences in capillary height for CWD negative lymph node (neg) (n = 8, average: 42.0 mm, stdev: 1.1 mm), misfolded solutions from CWD positive lymph node (pos) (n = 8, average: 51.1 mm, stdev: 1.4 mm), and buffer only control (n = 8, average: 52.6 mm, stdev: 2.3 mm). ɑ-syn = recombinant human ɑ-syn substrate, PrP = recombinant hamster prion protein substrate. p = 1.2 × 10−6 and 2.1 × 10−9 for ɑ-syn and PrP, respectively (two sample T-test).
