Table 4 Median biomarker concentrations in uninfected and infected neonatal saliva
From: Ultrasensitive detection of six sepsis-associated proteins in neonatal saliva
Biomarker | Uninfected median and [IQR] (pg/mL), n = 22 | Infected median and [IQR] (pg/mL), n = 18 | Log hazards ratio | Std. error | z-value | p (two-tailed) | Power (1−β) |
|---|---|---|---|---|---|---|---|
CXCL6 | 170. [111.–536.] | 594 [189.–9870] | −1.71 | 0.491 | −4.18 | 2.98e−5 | 0.987 |
CCL20 | 33.5 [20.9–92.6] | 188 [37.1–3048] | −1.36 | 0.386 | −3.52 | 4.28e−4 | 0.941 |
SAA1 | 762 [774.–1814] | 2470 [774.–27179] | −1.33 | 0.399 | −3.33 | 8.58e−4 | 0.915 |
CXCL12 | 42.0 [65.1–99.8] | 42.0 [65.1–74.3] | −0.013 | 0.332 | −0.039 | 0.970 | 4.62e−3 |
LBP | 767 [450.–3.48e3] | 2230 [450.–1.39e4] | −0.631 | 0.336 | −1.88 | 0.060 | 0.468 |
Resistin | 30.9 [19.8–512.] | 240. [19.8–7.88e3] | −0.313 | 0.330 | −0.950 | 0.343 | 0.154 |
Total protein (mg/mL) | 13.7 [13.4–14.8] | 13.6 [12.6–15.8] | −0.218 | 0.329 | −0.66 | 0.508 | 0.093 |