Table 6 Biomarker median relative abundance in uninfected and septic neonatal saliva

From: Ultrasensitive detection of six sepsis-associated proteins in neonatal saliva

Biomarker

Uninfected median and [IQR], n = 22

Infected median and [IQR], n = 18

Log hazard ratio

Std. error

z-value

p (two-tailed)

Power (1−β)

CXCL6

1.23e−11 [8.40e−12 – 4.48e−11]

4.46e−11 [1.34e−11 – 7.71e−10]

−1.71

0.411

−4.17

3.02e−5

0.987

CCL20

2.47e−12 [1.54e−12 – 9.04e−12]

1.31e−11 [2.91e−12 – 2.3e−10]

−1.56

0.390

−4.01

6.10e−5

0.980

SAA1

5.62e−11 [5.60e−11 – 1.31e−10]

1.76e−10 [5.93e−11 – 2.16e−9]

−1.71

0.411

−4.17

3.01e−5

0.987

CXCL12

3.11e−12 [4.73e−12 – 7.23e−12]

3.16e−12 [4.64e−12 – 5.81e−12]

0.018

0.320

0.057

0.954

0.007

LBP

5.58e−11 [3.33e−11 – 2.59e−10]

1.60e−10 [3.67e−11 – 9.14e−10]

−0.779

0.337

−2.31

0.021

0.637

Resistin

2.29e−12 [1.45e−12 – 3.74e−11]

1.96e−11 [1.50e−12 – 5.78e−10]

−0.359

0.328

−1.10

0.273

0.193

  1. Relative abundance values were calculated by taking the observed salivary protein concentration and dividing by the total protein concentration in the saliva. Medians and interquartile ranges (IQR) are reported for uninfected (n = 22) and infected (n = 18) neonates. Significance level is reported as the p-value of the interval-censored parametric proportional hazards model, which accounts for data censoring at the LOD or ULOQ.