Fig. 1: Schematic illustration of the two p-FLISA methods for RNA detection.
From: Plasmon-enhanced bioassay for amplification-free detection and quantification of SARS-CoV-2 RNA

Method I: RNA/DNA hybrids are captured by S9.6 antibodies. Subsequently, biotinylated S9.6 antibody serves as a detection element that binds to the captured RNA/DNA hybrid. Method II: RNA/DNA hybrid is captured by S9.6 antibodies. The complementary DNA probe, which is biotinylated, serves as the detection element.