Fig. 5: Leveraging the FBR for vascular and bone tissue engineering applications. | npj Biomedical Innovations

Fig. 5: Leveraging the FBR for vascular and bone tissue engineering applications.

From: Don’t judge an implant by its cover: how the foreign body response and fibrotic capsule might be harnessed for good

Fig. 5

Macroscopic photos showing the silicone rod-based implant (A) and the harvested Biotube 2 months post-implantation in the dorsal subcutaneous pouch of a rabbit (B). The Biotube was then implanted in a rabbit carotid artery (C) and harvested and imaged after 12 weeks (D). A schematic showing the process of the Masquelet technique (E). A Histology and Eosin (H&E) section of an induced membrane formed in response to implanted PMMA spacers in an ovine critical-sized bone defect model (F). All portions of this figure have either been republished with permission from the prior publisher121, under the Creative Commons Attribution License269, or from a modified Biorender template270.

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