Fig. 6: Schematic outlining the three in situ prevascularization approaches, which, in part, leverage the FBR to attract cells and encourage vasculature to form within an implanted scaffold material. | npj Biomedical Innovations

Fig. 6: Schematic outlining the three in situ prevascularization approaches, which, in part, leverage the FBR to attract cells and encourage vasculature to form within an implanted scaffold material.

From: Don’t judge an implant by its cover: how the foreign body response and fibrotic capsule might be harnessed for good

Fig. 6

These approaches are angiogenic ingrowth (A), the flap technique (B), and the AV-loop technique (C). Vasculature is represented in red (A, B). Veins are represented in dark blue and arteries are represented in red (C). Implanted materials are shown in gray, local tissue in orange, transplantation to the final defect site in light blue, and host vasculature at the final defect site in green (A–C). This figure has been adapted from a previously published figure with permission160.

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