Fig. 6: Synergistic antibacterial activity test. | npj Biomedical Innovations

Fig. 6: Synergistic antibacterial activity test.

From: Stepwise antibacterial strategy for orthopedic implants using bacteriophages on electrospun cefiderocol/PCl/Gt nanofibers over PEO-coated Mg3ZnCa

Fig. 6: Synergistic antibacterial activity test.

The profiles of CFD 6+ Ø, CFD 12+ Ø, CFD 24+ Ø co-release, compared to CFD 6, CFD 12, CFD 24 release, and antibacterial activity of ZX31PEO tracked over 24 h against E. coli. Each column represents the CFU of remaining viable bacteria over 24 h of treatment with cefiderocol alone, phage alone at 108 PFU/mL, or cefiderocol-phage combinations. Error bars represent the standard deviation (SD) of the mean. Data represent mean ± standard deviation (n = 4). CFD cefiderocol, Φ bacteriophage, GC growth control. The asterisk (*) indicates no CFUs detected (no bacterial growth observed).

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