Fig. 2: Associations Between DCTclock Performance and Mini-Cog Cognitive Impairment Status.
From: Digital clock assessment in South Asian setting: pilot study

A Odds ratios for cognitive impairment by DCTclock metrics. B. Odds Ratios for Cognitive Impairment DCTclock total score categories. (A) Forest plot showing unadjusted and adjusted odds ratios (ORs) with 95% confidence intervals (CIs) for Mini-Cog impairment (Mini-Cog score ≤2 vs. ≥3) by overall and subdomain DCTclock metrics. The DCTclock total score and subdomains (Drawing Efficiency, Information Processing, Simple Motor, and Spatial Reasoning) were analyzed separately under Command and Copy conditions. All continuous exposures were scaled by their interquartile range (IQR). Blue lines represent unadjusted models and black lines represent models adjusted for age category, sex, and education. ORs below 1.0 indicate that better cognitive performance is associated with lower odds of impairment. B Forest plot displaying associations between Mini-Cog impairment and categorical DCTclock scores based on (i) U.S. FDA-cleared thresholds (<60, 60–74, ≥75) and (ii) a data-derived cutpoint using Youden’s index from the ROC curve. The ≥75 group (FDA) and “Normal” group (Youden) were used as reference categories. Blue lines represent unadjusted models and black lines represent models adjusted for age category, sex, and education.