Table 3 Chosen operating points for the various organisms tested. In order to reduce the number of false positives, a specificity of 99.95% is typically chosen (* for E. coli a lower specificity of 99.0% was chosen due to the small size of the known interaction set). The positive-to-negative ratios (PNR) of the test sets are also given

C. elegans

99.95

1∶15.1

E. coli

99.0*

1∶6.2

H. sapiens

99.95

1∶2.4

S. cerevisiae

99.95

1∶2.3

S. pombe

99.95

1∶33.9