Table 5 Percentages of S. pombe, C. elegans and H. sapiens pairs in which both partners share the same GO SLIM annotation as well as third party interactions. (a) Results for 100,000 random S. pombe pairs. (b) Results for 2,951 previously known S. pombe interactions from BioGRID. (c) Results for our 9,009 S. pombe predicted interactions. (d) Results for 100,000 random C. elegans pairs. (e) Results for 6,607 previously known C. elegans interactions from BioGRID. (f) Results for our 37,572 C. elegans predicted interactions. (g) Results for 100,000 random H. sapiens pairs. (h) Results for 41,678 previously known H. sapiens interactions from BioGRID. (i) Results for our 1,056 H. sapiens predicted interactions
From: Short Co-occurring Polypeptide Regions Can Predict Global Protein Interaction Maps
Derived from GO annotation | |||||
|---|---|---|---|---|---|
Cellular Component (CC) | Molecular Function (MF) | Biological Process (BP) | CC & MF & BP | Third Party Interaction | |
(a) Random S. Pombe pairs | 32.6% | 2.4% | 7.3% | 1.0% | 0.032% |
(b) Previously detected S. Pombe interactions | 79.0% | 53.9% | 54.2% | 29.9% | 76.5% |
(c) Predicted S. Pombe Interactions | 61.8% | 39.9% | 34.5% | 18.9% | 36.2% |
(d) Random C. elegans pairs | 1.1% | 2.4% | 4.8% | 0.2% | 0.08% |
(e) Previously detected C. elegans interactions | 9.7% | 44.6% | 48.5% | 4.2% | 28.8% |
(f) Predicted C. elegans Interactions | 4.7% | 30.2% | 30.2% | 1.8% | 6.8% |
(g) Random H. sapiens pairs | 31.7% | 32.7% | 28.2% | 11.3% | 0.3% |
(h) Previously detected H. sapiens interactions | 82.5% | 90.1% | 82.2% | 67.7% | 59.2% |
(i) Predicted H. sapiens interactions | 91.2% | 92.9% | 88.9% | 83.2% | 45.3% |
