Figure 3
Phylogenetic analysis of the functional regions of streptococcal GTF.
Phylogenetic trees based on the gene encoding the catalytic region (A), the deduced amino acid sequence of the catalytic region (B), the gene encoding the first unit of the glucan-binding region constructed of 6 direct repeat units (C) and the deduced amino acid sequence of the first unit of the glucan-binding region were constructed by the neighbor-joining (NJ) method. In A and B, the streptococcal gtf gene family can be classified into 3 clusters: the water-soluble glucan synthesizing group (WSG), the water-insoluble glucan synthesizing group (WIG) and the intermediate group (INT). In D, GTFs from same or closely related species could be divided into the same cluster. The value on each branch is the estimated confidence limit (expressed as a percentage) for the position of the branches, as determined by bootstrap analysis. Only values exceeding 50% are shown. The scale bar ([NJ] distance) represents a 5% difference in nucleotide sequence.
