Figure 3
From: Network rewiring is an important mechanism of gene essentiality change

Functional enrichment analysis of essentiality changing genes.
(a) Comparison Biological processes of N2E, E2N and N2N genes with those of E2E genes in yeast and mouse. (b) Enrichment of biological processes in the four phenotypic groups. Gene ontology terms that are significantly enriched (p < 0.001) in N2E genes are presented. (c) Network connections of Map2k1 in yeast, worm, chicken and mouse. Interaction partners Map2k1 in yeast (left) and mouse (right) are depicted with the orthologs connected by dotted lines.