Table 1 Developmental processes of N2E genes in mouse
From: Network rewiring is an important mechanism of gene essentiality change
Developmental process | N2E genes |
|---|---|
blastocyst development | Cul3, Smarcb1, Ada, Sp3, Junb |
mammary gland development | Phb2, Atp7b |
in utero embryonic development | Prmt1, Sin3a, Cul3, Slc30a1, Ccnb2, Smarcb1, Msh2, Ube2a, Mapk1, Myo1e, Mecom, Sp3, Ccnb1, Plcg1, Junb, Lig4, Fgfr1, Ada, Hsf1, Map2k1 |
immune system development | Exo1, Msh2, Maea, Ung, Sp3, Rps19, Slc11a2, Xrcc6, Lig4, Blm, Sgpl1, Msh6, G6pdx, Ccnb2, Mlh1, Myo1e, Tcea1, Ada, Hells, Sod2, Dnaja3 |
hemopoietic or lymphoid organ development | G6pdx, Ccnb2, Msh2, Myo1e, Maea, Sp3, Rps19, Slc11a2, Lig4, Blm, Sgpl1, Tcea1, Ada, Hells, Sod2, Dnaja3 |
positive regulation of developmental process | Hmgb1, Junb, Lig4, Xrcc6, Fgfr1, Ada, Map2k1, Mapk14 |
tube development | Phb2, Hmgb1, Timeless, Sp3, Ppp3r1, Ptges3, Fgfr1, Ada |
gland development | Phb2, Atp7b, Fgfr1 |
chordate embryonic development | Msh2, Ube2a, Phgdh, Sp3, Junb, Lig4, Fgfr1, Map2k1, Prmt1, Sin3a, Cul3, Slc30a1, Ccnb2, Smarcb1, Mapk1, Myo1e, Mecom, Ccnb1, Plcg1, Ada, Hsf1, Atm |
embryonic development ending in birth or egg hatching | Msh2, Ube2a, Phgdh, Sp3, Junb, Lig4, Fgfr1, Map2k1, Prmt1, Sin3a, Cul3, Slc30a1, Ccnb2, Smarcb1, Mapk1, Myo1e, Mecom, Ccnb1, Plcg1, Ada, Hsf1, Atm |
blood vessel development | Myo1e, Mapk1, Sphk2, Vezf1, Junb, Ppap2b, Sgpl1, Atg5, Fgfr1, Map2k1, Mapk14 |
