Figure 5
From: Visualizing Brain Inflammation with a Shingled-Leg Radio-Frequency Head Probe for 19F/1H MRI
In Vivo 1H (grey) and Post Mortem 19F MR(red) Images.
EAE was induced in SJL/J mice and 160 nm 19F-rich nanoparticles (5 μmoles 19F) were administered daily, starting from day 5 following immunization.(A) Horizontal and (B) sagittal slices of a 3D TurboRARE-scan for in vivo 1H (grayscale): TR = 1500 ms, TE = 53 ms, FOV = (40 × 16 × 16) mm3, Matrix = 320 × 128 × 128, RARE Factor = 16, NEX = 1 (scan time = 25 min) and for ex vivo 19F (red): TR = 1000 ms, TE = 6 ms, FOV = (40 × 16 × 16) mm3, Matrix = 100 × 40 × 40, zero fill acceleration 2, RARE Factor = 40, NEX = 2048 (scan time = 690 min).
