Figure 1 | Scientific Reports

Figure 1

From: Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction

Figure 1

Nm23-H1 and h-Prune gene expression and NBL overall survival.

(a) NME1 expression in human NBL tissues (88 samples) compared to normal adrenal gland (13 samples) searched through a public database (Versteeg database). (b) H-prune expression in human NBL tissues compared to normal adrenal gland (Versteeg database). (c) In the Essen Affymetrix database, Nm23-H1 was detected with a probe which does not discriminate between Nm23-H1 and Nm23-H2. High expression of Nm23-H1/H2 in tumors promotes worse overall survival. (d) High expression of h-Prune in NBL tissues shows a trend towards worse overall survival that does not reach significance.

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