Figure 3
From: Skin Stem Cell Hypotheses and Long Term Clone Survival – Explored Using Agent-based Modelling
Evolution of a single lineage over three years in scenarios (1) and (3).
In the asymmetric division case, the offspring forms a column around the stem cell similar to that described as an EPU29. The stem cell is surrounded by several progeny in the basal compartment. The differentiated cells are localised in this area. In contrast, individual colony shape changes dramatically in the PAS hypothesis, with substantial lateral movements20.
