Figure 1
From: CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function
Overlay of the murine (red) and human (blue) CSF1R autoinhibited kinase domain shows significant sequence homology.
YASARA-predicted proteins show a sequence similarity of 95.74% and RMSD of 0.365 Ã…. Locations of the HDLS mutations1 are shown in yellow.
