Figure 6
From: Modifying cellular properties using artificial aptamer-lipid receptors
Tenascin-C modified cells are better able to aggregate to tenascin-C containing cells.
(A) Flow cytometry results show aggregation of TNC-AR modified CEM with MDA-MD-231 cells. A population of cells exhibiting both FL1 and FL4 signals can be seen when TNC AALR-modified CEM cells were allowed to aggregate with MDA-MB-231 at 4°C. (B) 55% aggregation was observed for TNC-AR modified cells compared to 21% for Library-AR modified cells at 10:1 (CEM:MDA-MB-231) ratio. 45% aggregation was observed for TNC-AR modified cells at a 5:1 ratio and 9.2% aggregation for Library-AR modified cells.
