Figure 2 | Scientific Reports

Figure 2

From: Network Analysis Reveals Functional Cross-links between Disease and Inflammation Genes

Figure 2

Topological analysis of the DIN.

The number of overlapping genes among the nodes of the PPI network, disease genes and inflammation genes are shown in (A). Black arrow indicates the three categories of inter-genes, inflammation genes only and disease genes only in the DIN. (B) Degree distribution for all the nodes in the DIN is plotted on the x-axis and the numbers of genes are plotted on the y-axis. (C) Degree distribution for three categories of nodes in the DIN. Significance tests were based on the Wilcoxon's Rank-Sum Test and p values for comparisons between inter-genes and disease genes only and between inter-genes and inflammation genes only are both less than 0.01. Clustering coefficients (D) and topological coefficients (E) for all the nodes in the DIN are plotted on the y-axis and the corresponding degrees are plotted on the x-axis.

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