Figure 2
From: Oral administration of inosine produces antidepressant-like effects in mice
Inosine is increased in the brain after its single oral administration.
(a) Typical chromatograms of HPLC. The upper image is a chromatogram of a standard mixture and the lower one is that of the supernatant of homogenized brain in untreated mouse. (b) One hour after administration of inosine (0.33 mg/g of body weight), mice were sacrificed and cerebral hemisphere was subjected to HPLC analysis (n = 10 per group). Data represent mean ± s.e. *P < 0.05.
