Table 2 Power calculations to detect Genetic association

From: Evaluation of Genetic Association of the INK4 Locus with Primary Open Angle Glaucoma in East Indian Population

  

Wiggs et al. 2012(3146 cases, 3487 controls)

Fan B.J. et al 2011(536 cases, 336 controls)

East Indian population(350 cases, 354 controls)

SNP

Allele

POWER (%)

Allele frequency

POWER (%)

Allele frequency

POWER (%)

Allele frequency

rs1063192

A

100

0.57

90.32

0.58

81.21

0.75

  1. Note: Power calculations were done for ‘A’ allele by keeping relative risk as 1.8 (Homozygous genotype) and 1.2 (Heterozygous genotype) calculated from genotype data given by Fan B.J. et al, 2011and allele frequency were taken from respective studies ( Supplementary Table S1 ).
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