Table 1 Performance comparison of our work with other existing tools for H. sapiens. The performance was evaluated using six measures such as MCC, ACC, SEN, SPE, PRE and AUC, based on the three tests: benchmark (our method is based on 5-fold cross-validation), independent test and independent test datasets with negatives selected on the same proteins

Datasets	Tools	MCC	ACC	SEN	SPE	PRE	AUC
Benchmark test	PLMLA	0.274	0.667	0.560	0.721	0.503	0.691
	Phosida	0.191	0.618	0.542	0.657	0.444	0.631
	LysAcet	0.131	0.579	0.540	0.598	0.405	0.591
	ensemblePail	0.107	0.565	0.529	0.583	0.391	0.564
	PSKAcePred	0.187	0.602	0.589	0.608	0.432	0.622
	BRABSB	0.345	0.694	0.630	0.726	0.538	0.675
	Our Work	0.409	0.709	0.736	0.695	0.549	0.794
Independent test	PLMLA	0.312	0.672	0.633	0.692	0.515	0.701
	Phosida	0.141	0.599	0.491	0.655	0.424	0.599
	LysAcet	0.089	0.558	0.512	0.582	0.388	0.552
	ensemblePail	0.065	0.558	0.457	0.610	0.378	0.537
	PSKAcePred	0.169	0.591	0.583	0.595	0.427	0.602
	BRABSB	0.278	0.655	0.612	0.678	0.496	0.653
	Our Work	0.325	0.664	0.694	0.648	0.505	0.756
Independent test with negative set selected on the same Protein	PLMLA	0.296	0.648	0.633	0.663	0.667	0.689
	Phosida	0.136	0.568	0.553	0.583	0.585	0.597
	LysAcet	0.120	0.558	0.503	0.616	0.583	0.552
	ensemblePail	0.076	0.535	0.457	0.618	0.560	0.534
	PSKAcePred	0.111	0.556	0.553	0.558	0.571	0.556
	BRABSB	0.275	0.637	0.612	0.663	0.659	0.645
	Our Work	0.214	0.600	0.482	0.725	0.652	0.606

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