Table 3 A summary of feature type, annotation and dimensionality. Features can be classified into four major categories: sequence-derived features, predicted secondary structure, functional annotation and functional features
Feature type | Annotation | Dimensionality |
|---|---|---|
Sequence | PSSM (PSI-BLAST) | 260 |
| Â | AAindex | 7280 |
| Â | Physicochemical properties of the whole protein | 10 |
| Â | Evolutionary conservation score | 13 |
Predicted secondary structure | SABLE score | 39 |
| Â | DISOPRED score | 26 |
| Â | SpineX score | 221 |
Functional Annotation | Domain | 13 |
| Â | Nucleotide binding | 13 |
| Â | Disulfide bond | 13 |
| Â | Posttranslational modified residue (acetylation is removed) | 13 |
| Â | Glycosylation | 13 |
| Â | Active site | 13 |
| Â | Natural variant | 13 |
| Â | Metal ion binding site | 13 |
| Â | Binding site | 13 |
Functional Features | Gene ontology | 3 |
| Â | KEGG pathway | 1 |
| Â | Pfam | 1 |
| Â | InterPro | 1 |
| Â | Protein-protein interaction | 1 |
