Figure 1
Phylogenetic tree of the RyR and IP3R families.
A multiple alignment of TcRyR and TcIP3R amino acid sequences with representative RyR and IP3R isoforms was performed and used as the input for phylogenetic analysis. The Neighbor-joining tree was generated using MEGA5 with 1000 bootstrapping. RyR sequences are obtained from the following GenBank entries: DJ085056 for Bombyx mori (sRyR); AET09964 for Plutella xylostella (PxRyR); BAA41471 for Drosophila melanogaster (DmRyR); AFK84957 for Bemisia tabaci (BtRyR); JQ799046 for Cnaphalocrocis medinalis (CmRyR); AHW99829 for Sogatella furcifera (SfRyR); AHW99830 for Leptinotarsa decemlineata (LdRyR); AHY02115 for Bactrocera dorsalis (BdRyR); AGH68757 for Ostrinia furnacalis (OfRyR); KF306296 for Nilaparvata lugens (NlRyR); BAA08309 for Caenorhabditis elegans (CeRyR); NM_-000540 for Homo sapiens RyR1 (HsRyR1); NM_001035 for Homo sapiens RyR2 (HsRyR2); NM_001243996 for Homo sapiens RyR3 (HsRyR3). IP3R sequences are obtained from the following GenBank entries: AAN13240 for D. melanogaster (DmIP3R); EAT33105 for Aedes aegypti(AaIP3R); XP_004923625 for B. mori (BmIP3R); XP_006564780 for Apis mellifera (AmIP3R); CCD63765 for C. elegans (CeRyR); AAT47836 for Oikopleura dioica(OdIP3R); AAC61691 for Panulirus argus (PaIP3R); NP_001161744 for Homo sapiens IP3R1 (HsIP3R1); NP_002214 for Homo sapiens IP3R2 (HsIP3R2); NP_002215 for Homo sapiens IP3R3 (HsIP3R3).
