Figure 4
From: Dissecting the Human Protein-Protein Interaction Network via Phylogenetic Decomposition

Age homogeneity and functional similarity of PPI dyads.
(a) Composition of PPI dyads classified by the difference in age between the two paired proteins. All PPIs: all PPI dyads from the human PPI network; Complex PPIs: the PPIs within protein complexes. (b) Profile of functional similarity among PPI dyads. Cell values indicate the median. Color scheme (red-to-green) represents the magnitude of similarity degree (high-to-low). GOBP/GOMF: similarities based on the Gene Ontology namespace of the Biological Process/Molecular Function.