Table 4 Inhibition rate and CI of sample and compound combinations (n = 3)

From: System-level Study on Synergism and Antagonism of Active Ingredients in Traditional Chinese Medicine by Using Molecular Imprinting Technology

Combinations

CA*

SCO*

IsoB *

S2*

S3*

RDN*

Inhibition rate (%)

CI

CA + S2

0.8

-

-

80.0

-

-

67.25 ± 2.74

0.855

 

1.7

-

-

80.0

-

-

70.72 ± 0.69

0.793

 

3.3

-

-

80.0

-

-

72.65 ± 0.99

0.773

 

6.6

-

-

80.0

-

-

75.28 ± 0.12

0.761

 

13.3

-

-

80.0

-

-

93.58 ± 0.50

0.299

CA + RDN

4.8

-

-

-

-

104.0

54.13 ± 4.10

0.967

 

6.8

-

-

-

-

104.0

55.48 ± 5.26

0.983

 

13.6

-

-

-

-

104.0

67.33 ± 2.31

0.722

 

27.3

-

-

-

-

104.0

72.51 ± 1.29

0.793

 

54.6

-

-

-

-

104.0

77.50 ± 3.32

0.962

IsoB + S2

-

-

0.6

80.0

-

-

73.22 ± 3.84

0.708

 

-

-

1.2

80.0

-

-

74.21 ± 3.09

0.688

 

-

-

2.5

80.0

-

-

75.75 ± 3.58

0.657

 

-

-

5.0

80.0

-

-

78.38 ± 2.08

0.606

 

-

-

10.0

80.0

-

-

87.57 ± 1.97

0.408

IsoB + RDN

-

-

3.6

-

-

104.0

49.03 ± 6.68

1.020

 

-

-

8.4

-

-

104.0

50.71 ± 13.40

0.993

 

-

-

13.1

-

-

104.0

51.84 ± 9.41

0.989

 

-

-

26.1

-

-

104.0

62.66 ± 3.59

0.671

 

-

-

52.2

-

-

104.0

65.27 ± 0.44

0.718

SCO + S2

-

19.5

-

80.0

-

-

36.56 ± 16.09

2.532

 

-

39.0

-

80.0

-

-

41.61 ± 14.06

2.829

 

-

78.1

-

80.0

-

-

61.65 ± 16.06

2.286

 

-

156.1

-

80.0

-

-

82.43 ± 5.06

1.656

 

-

312.2

-

80.0

-

-

84.57 ± 4.89

2.487

SCO + S3

-

19.5

-

-

119.7

-

82.56 ± 1.98

0.321

 

-

39.0

-

-

119.7

-

85.01 ± 0.96

0.398

 

-

78.1

-

-

119.7

-

88.43 ± 0.96

0.506

 

-

156.1

-

-

119.7

-

91.01 ± 0.21

0.716

 

-

312.2

-

-

119.7

-

93.78 ± 1.16

0.981

SCO + RDN

-

19.5

-

-

-

104.0

73.46 ± 2.26

0.517

 

-

39.0

-

-

-

104.0

82.96 ± 4.37

0.438

 

-

78.1

-

-

-

104.0

84.98 ± 0.97

0.631

 

-

156.1

-

-

-

104.0

90.84 ± 0.73

0.715

 

-

312.2

-

-

-

104.0

94.57 ± 0.13

0.863

  1. *Concentration units of CA, SCO and IsoB were μM. Concentration units of S2, S3 and RDN were μg mL-1.