Table 1 Known phenotypes of GPR43 knockout mice

Maslowski et al. 2009¹

Exacerbated colitis, arthritis and asthma

Reduced neutrophil recruitment

Sina et al. 2009²

Reduced colitis

Increased neutrophil recruitment

Kim et al. 2013³

Reduced colitis

Reduced ERK and p38 activation in epithelial cells

Smith et al. 2013⁴

Exacerbated colitis

Reduced Treg cell count

Ge et al. 2008⁵³

Increased lipolysis and plasma free fatty acids

Bjursell et al. 2011⁶

Improved glucose control and reduced body fat mass on a high fat diet

Tolhurst et al. 2012⁷

Impaired glucagon-like peptide-1 secretion and glucose tolerance

Kimura et al. 2013⁸

Increased fat accumulation and obesity on a normal diet