Figure 2
From: Discordance of DNA Methylation Variance Between two Accessible Human Tissues
Tissue specific DNA methylation was enriched in regions of low CpG density.
(a) Probewise tissue specific DNA methylation was evaluated by t-test p-value and Δβ. Categories of differentially methylated probes were identified by color. 12.1% of all CpG loci (red) had p-value < 0.001 and Δβ > 40% and 17.8% of CpG loci (yellow) had p-value < 0.001 and Δβ > 20%; (b) Distribution of intra-class correlation coefficient (ICC) for high, intermediate and low CpG density regions. Probes residing in regions of low CpG density had higher proportion of ICC values near −1.0.
