Figure 2 | Scientific Reports

Figure 2

From: Hematologic and immunological characteristics of Henoch-Schönlein purpura in rat and rabbit models induced with ovalbumin based on type III hypersensitivity

Figure 2

Routine blood, serum immunoglobulin and complement levels in animals and pediatric patients.

(A, B) Routine blood analyses in model rats and rabbits, respectively. WBC, Gran and Gran% increased, while LYMPH% decreased and there was no significant change in PLT in both animals compared to the controls. LYMPH decreased in HSP rats, while EOS and EOS% increased in HSP rabbits. (C, D, E) The changes of serum immunoglobulin and complement level in HSP rats, rabbits and pediatric patients, respectively. IgA level increased, while C3 and C4 levels decreased in HSP animals and patients compared to controls. IgG levels increased in HSP rats and patients and decreased in HSP rabbits. IgE levels increased in HSP patients and did not change in the model animals. n = 10–18. * P < 0.05 and **P < 0.01 vs. controls.

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