Table 1 Values of switching rates between growth and stop states obtained by fitting experimental data in Fig. 2 and the corresponding probability of growth as defined in Eq. (16)
From: A monomer-trimer model supports intermittent glucagon fibril growth
[Gtot] (mg/mL) | ks→g (min−1) | kg→s (min−1) | p G |
|---|---|---|---|
1.5 | 0.113 ± 0.025 | 0.0268 ± 0.0005 | 0.808 ± 0.034 |
3 | 0.037 ± 0.002 | 0.0215 ± 0.0003 | 0.632 ± 0.015 |
6 | 0.091 ± 0.006 | 0.0292 ± 0.0012 | 0.756 ± 0.014 |
10 | 0.046 ± 0.020 | 0.0113 ± 0.0002 | 0.805 ± 0.069 |
15 | 0.306 ± 0.096 | 0.0444 ± 0.0024 | 0.873 ± 0.035 |
