Table 2 Comparison of diacetyl production by different microorganisms
From: Production of diacetyl by metabolically engineered Enterobacter cloacae
Strain | Engineering strategy | Diacetyl (g/L) | Yield (mol/mol) | Productivity (g/(L·h)) | Reference |
|---|---|---|---|---|---|
L. lactis | Inactivation of ALDC, overexpression of NADH oxidase | 0.38 | 0.16 | 0.03 | |
L. lactis | Random mutagenesis | 0.52 | –a | 0.02 | |
L. rhamnosus | WT | 0.6 | 0.2 | 0.06 | |
E. aerogenes | UV mutation and medium optimization | 1.35 | 0.03 | –α | |
L. lactis | Inactivation of ALDC, overexpression of NADH oxidase | 0.36 | 0.12 | 0.03 | |
C. glabrata | Overexpression of ALS, inactivation of ALDC and DR, medium optimization | 4.70 | 0.10 | 0.07 | |
E. cloacae | Inactivation of ALDC and DR, Fe3+ addition | 1.45 | 0.21 | 0.13 | This study |
