Figure 16
Comparative bar diagram showing changes in turbidity of aggregated WtAS samples in the presence and absence of compounds 1, 3, 6 and 15.
WtAS (210 µM) was co-incubated with equimolar concentration of compound 1, 3, 6 and 15 for 30 days. The changes in turbidity were monitored by turbidity assay. 5 µl samples of WtAS samples were added to 145 µl of aggregation buffer and absorbance at 360 nm was recorded using UV-Vis spectrophotometer. Increase in turbidity was calculated by subtracting the turbidity at day 0. Results are mean of three independent experiments done in duplicate. $ p < 0.0001 control vs compound 6.
