Figure 3

CDR3 characterization of TCRβ
(a) A representative TCRβ CDR3 sequence spectratype. The sequences within each length bin were color-coded based on their J gene use. The inset shows all CDR3 sequences using J2-1, with a length of 13 amino acids and the number of times that each of these sequences was observed in the data. (b) Frequency histograms of TCRβ CDR3 sequences. (c) Sampling-resampling techniques were used to estimate the CDR3 repertoire size (described in “data analysis” of the Methods).